C9H11FN2O5 Uridine, 2′ -deoxy-2′ -fluoro- (7CI, 8CI, 9CI, ACI)

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Nambala ya Registry ya CAS

784-71-4

H228

Zofunika Zathupi	Mtengo	Mkhalidwe
Kulemera kwa Maselo	246.19	-
Melting Point (Zoyeserera)	149-150 ° C	-
Kachulukidwe (Zonenedweratu)	1.63±0.1 g/cm3	Kutentha: 20 ° C;Press: 760 Torr
pKa (Zonenedweratu)	9.39±0.10	Kutentha Kwambiri kwa Acid: 25 ° C

Canonical SMILES

O=C1C=CN(C(=O)N1)C2OC(CO)C(O)C2F

Isomeric AMAmwetulira

F[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C=C2

InChi

InChI= 1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4, 6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1

InChi Key

UIYWFOZZIZEEKJ-XVFCMESISA-N

4 Maina ena a chinthu ichi

2'-Deoxy-2'-fluorouridine (ACI);1-(2-Deoxy-2-fluoro- β -D-ribofuranosyl)uracil;2'-Fluoro-2' -deoxyuridine;2 - Fluoro-uridine

Katundu zilipo
Kuwala ndi Kubalalika
Kutentha

Katundu	Mtengo	Mkhalidwe	Gwero
Mphamvu Yozungulira ya Optical	+ 52 deg	Zosungunulira: Madzi;: 589.3 nm;Kutentha: 20 ° C	(1) CAS

(1) Codington, John F.;Journal of the American Chemical Society, (1961), 83, 5030-1, CAplus

(1) Mercer, John R.;Journal of Medicinal Chemistry, (1989), 32 (6), 1289-94, CAplus

(2) Codington, John F.;Journal of the American Chemical Society, (1961), 83, 5030-1, CAplus

(3) Van Aerschot, A.;Bulletin des Societes Chimiques Belges (1989), 98(12), 937-41, CAplus

Spectra ilipo
1H NMR
13 C NMR
Hetero NMR
IR
Misa
Raman
UV ndi Zowoneka

Katundu zilipo
Zachilengedwe
Chemical
Kuchulukana
Lipinski
Zogwirizana ndi Kapangidwe

Katundu	Mtengo	Mkhalidwe	Gwero
logP	-0.538±0.456	Kutentha: 25 ° C	(1) ACD
Mass Intrinsic Solubility	4.9g/l	Kutentha: 25 ° C	(1) ACD
Misa Solubility	4.9g/l	pH 1;Kutentha: 25 ° C	(1) ACD
Misa Solubility	4.9g/l	pH 2;Kutentha: 25 ° C	(1) ACD
Misa Solubility	4.9g/l	pH 3;Kutentha: 25 ° C	(1) ACD
Misa Solubility	4.9g/l	pH 4;Kutentha: 25 ° C	(1) ACD
Misa Solubility	4.9g/l	pH 5;Kutentha: 25 ° C	(1) ACD
Misa Solubility	4.9g/l	pH 6;Kutentha: 25 ° C	(1) ACD
Misa Solubility	4.9g/l	pH 7;Kutentha: 25 ° C	(1) ACD
Misa Solubility	5.2g/L	pH 8;Kutentha: 25 ° C	(1) ACD
Misa Solubility	6.9g/l	pH 9;Kutentha: 25 ° C	(1) ACD
Misa Solubility	25g/l	pH 10;Kutentha: 25 ° C	(1) ACD
Misa Solubility	4.9g/l	Madzi Osasunthika pH 5.53;Kutentha: 25 ° C	(1) ACD
Molar Intrinsic Solubility	0.020 mol / L	Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.020 mol / L	pH 1;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.020 mol / L	pH 2;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.020 mol / L	pH 3;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.020 mol / L	pH 4;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.020 mol / L	pH 5;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.020 mol / L	pH 6;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.020 mol / L	pH 7;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.021 mol / L	pH 8;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.028 mol / L	pH 9;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.10 mol / L	pH 10;Kutentha: 25 ° C	(1) ACD
Molar Solubility	0.020 mol / L	Madzi Osasunthika pH 5.53;Kutentha: 25 ° C	(1) ACD
Kulemera kwa Maselo	246.19
pKa	9.39±0.10	Kutentha Kwambiri kwa Acid: 25 ° C	(1) ACD

Katundu	Mtengo	Mkhalidwe	Gwero
Ma Bond Osinthasintha Mwaulere	4		(1) ACD
H Olandira	7		(1) ACD
H Opereka	3		(1) ACD
H Chiwerengero cha Wopereka / Wolandira	10		(1) ACD
logP	-0.538±0.456	Kutentha: 25 ° C	(1) ACD
Kulemera kwa Maselo	246.19