Sulfamethazine

Sulfadiazine ndi mankhwala a sulfanilamide omwe ali ndi antibacterial spectrum ofanana ndi sulfadiazine. Lili ndi antibacterial effect pa enterobacteriaceae bacteria monga non-zymogenic Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, etc. Neisseria gonorrhoea, Neisseria meningitidis ku Haemoenza ndi Haemoenza. Komabe, kukana kwa bakiteriya kwa mankhwalawa kunakula, makamaka mabakiteriya a streptococcus, Neisseria ndi Enterobacteriaceae. Ma sulfonamides ndi ma bacteriostatic agents of wide-spectrum, ofanana mu kapangidwe ka p-aminobenzoic acid (PABA), omwe amatha kupikisana nawo pa dihydrofolate synthetase mu mabakiteriya, motero amalepheretsa PABA kugwiritsidwa ntchito ngati zopangira kupanga folate yofunikira ndi mabakiteriya ndikuchepetsa kuchuluka kwa mabakiteriya. metabolically yogwira tetrahydrofolate. Chotsatirachi ndi chinthu chofunika kwambiri pakupanga purines, thymidine nucleosides ndi deoxyribonucleic acid (DNA), choncho imalepheretsa kukula ndi kubereka kwa mabakiteriya.