Mapulogalamu Ofunika Osinthidwa Osinthidwa

Chiyambi

Ndege, nyumba yomanga ya ma acid acids (DNA ndi RNA), amatenga mbali yofunika kwambiri mu zolengedwa zonse. Mwa kusintha ma mamolekyu, asayansi sanatsegule kuchuluka kwa ntchito zomwe zingachitike pakufufuza ndi mankhwala. Munkhaniyi, tifufuza zina mwazofunikira zaZosinthidwa Nyeta.

Udindo Wosinthidwa Nyeta

Zosinthidwa zosinthidwa zimapangidwa ndikusintha kapangidwe ka zilengedwe, monga Adenosine, Gunosine, Cytidine, ndi Uridine. Zosintha izi zitha kuphatikizira kusintha kwa maziko, shuga, kapena zonse ziwiri. Kapangidwe kosinthika kumatha kupereka katundu watsopano ku ma nurcleosside, kumapangitsa kuti ikhale yoyenera pamapulogalamu osiyanasiyana.

Ntchito zazikulu

Kupeza Mankhwala:

Othandizira a anticancer: Kusintha kwa ma encleoside agwiritsidwa ntchito kukulitsa mankhwala osokoneza bongo a Anticancer. Mwachitsanzo, atha kupangidwa kuti alepheretse sca synthesi kapena kulinganiza maselo a khansa.

Othandizira a Antiviral: Osinthidwa kusinthidwa kwa ma encleosaides amagwiritsidwa ntchito popanga mankhwala osokoneza bongo omwe amatha kuletsa kuyambitsanso kwa mafakitale. Chitsanzo chodziwika bwino kwambiri ndikugwiritsa ntchito kusinthidwa kwa ma vavid-19 mrna.

Antibacterial othandizira a antibacterial: osinthidwa anticleoossides asonyezanso lonjezo pakukula kwa maantibayotiki atsopano.

Ma genetic engiinjiniya:

Katemera wa MRNA: Kusintha kwa ma encleoossides ndi zigawo zokhudzana ndi Mrna katemera, chifukwa amatha kukulitsa kukhazikika ndi imnogenicnicity wa MRNA.

Antistiete origonicles: mamolekyuluwa, omwe amapangidwa kuti azimangika kwa a MRNA, amatha kusinthidwa kuti azitha kusintha kukhazikika kwake komanso kudera.

Mankhwala othandizira: Zosinthidwa zosinthidwa zimatha kugwiritsidwa ntchito kupanga oligonicleotizides kwa gene mankhwala, monga kuwongolera chilema.

Zida Zofufuzira:

Ma nucleic acid Makafukufuku: Zosinthidwa ma enki osinthika zitha kuphatikizidwa mu ma proes omwe amagwiritsidwa ntchito mu maluso monga flurescence mu site hybridization (nsomba) komanso kupenda ma microray.

Aptamers: Acidic acid omwe ali pagululi amatha kusinthidwa kuti azimangika pazolinga zake, monga mapuloteni kapena mamolekyulu ang'onoang'ono, ndipo ali ndi mapulogalamu pakuzindikira.

Ubwino Wosinthidwa Zosinthidwa

Kukhazikika: Kusinthidwa kwa ma ewuni kumatha kukulitsa kukhazikika kwa ma acid a nuclec acid, kuwapangitsa kukhala osagwirizana ndi ma enzyme.

Kuchulukitsa: Zosintha zimatha kusintha momwe zidaliriridwira za eclevic ya ecclec, zomwe zimakuthandizani kuwerengera mwachidule mamolekyulu azachilengedwe.

Kulimbikitsidwa Kukweza kwa Ma cell: Kusinthidwa kwa ma cell etchulaid kumatha kupangidwa kuti akonzetse bwino ma cellular, kuwonjezera luso lawo m'mapulogalamu othandizira.

Mapeto

Kusintha kwa ma ewuni yasinthidwa kwasintha minda yosiyanasiyana, kuchokera ku matenda opezeka ndi mankhwala kupita ku genetic urmining. Kusintha kwawo komanso kuthekera kwawo kogwirizana ndi mapulogalamu enawa kumapangitsa zida zapamwamba kuti akatswiri azifufuza ndi zipatala. Pamene kamvedwe kathu ka machesi wa nyukiliya umapitilirabe, titha kuyembekeza kuwona zofunikira zochulukirapo za zosintha zosinthidwa mtsogolo.