C47H60N7O10P Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2- methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N N-bis (1-methylethyl)phosphoramidite] (ACI)

mankhwala

C47H60N7O10P Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2- methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N N-bis (1-methylethyl)phosphoramidite] (ACI)

Zambiri Zoyambira:


Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Tsatanetsatane wa Mankhwala

Nambala ya Registry ya CAS

251647-55-9

H302

Zofunika Zathupi Mtengo Mkhalidwe
Kulemera kwa Maselo 914.00 -
pKa (Zonenedweratu) 9.16±0.20 Kutentha Kwambiri kwa Acid: 25 ° C

Mayina Ena ndi Zizindikiritso

Canonical SMILES

N#CCCOP(OC1C(OC(N2C= NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OCCOC)COC(C=4C=CC=CC4)(C5=CC =C(OC)C=C5)C6=CC=C(OC)C=C6) N(C(C)C)C(C)C

Isomeric AMAmwetulira

C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@@ H](O1)N2C3=C(N=C2)C(=O)N=C(NC(C(C)C)=O)N3)(C4=CC=C (OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6

InChi

InChi= 1S/C47H60N7O10P/c1-30(2)43(55)51-46-50-42-39(44(56)52-46)49-29-53(42)45-41(60-27-26- 57-7)40(64-65(62-25-13-24-48)54( 31(3)4)32(5)6)38(63-45)28-61-47(33-14-11-10-12-15-33,34-16-20-3) 6(58-8)21-17-34)35-18-22-37(59-9)23-19-35/h10-12,14-23,29-32,38 ,40-41,45H,13,25-28H2,1-9H3,(H2,50,51,52,55,56)/t38-,40-,41-,45-,65?/m1/s1

InChi Key

LADCDGNEBIQAAU-SBCRAQIVSA-N

17 Maina ena a chinthu ichi

Guanosine, 5'-O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3′ - [2-cyanoethyl bis(1- methylethyl)phosphoramidite] (9CI); 17: PN: US20030212017 TSAMBA: 20 zotsatizana; 18: PN: US20030211606 TSAMBA: 20

adatengera kutsatizana; 19: PN: US20040005569 TSAMBA: 22 zotsatizana; 21: PN: US20040006030 TSAMBA: 23 zotsatizana; 21: PN: US20040014047 TSAMBA: 21 zotsatizana; 21: PN: US20040014049 TSAMBA: 21 zotsatizana; 22: PN: US20030198965 PAG

E: 20 zotsatizana; 22: PN: US20040005570 TSAMBA: 21 zotsatizana; 22: PN: US20040014048 TSAMBA: 21 zotsatizana;

22: PN: US20040014050 TSAMBA: 21 zotsatizana; 23: PN: US20040005565 TSAMBA: 17- 22 zotsatizana; 23: PN: US20040

014051 TSAMBA: 23 zotsatizana; 24: PN: US20040014699 TSAMBA: 21 zotsatizana; 25: PN: US20040006029 TSAMBA: 23 zotsatizana; 25: PN: WO03106645 TSAMBA: 73 zotsatizana; 96: PN: US20040005707 TSAMBA: 21 zotsatizana

Experimental Spectra

Spectra ilipo
13 C NMR
Hetero NMR

Zonenedweratu Katundu

Katundu zilipo
Zachilengedwe
Chemical
Lipinski
Zogwirizana ndi Kapangidwe

Zachilengedwe

Katundu Mtengo Mkhalidwe Gwero
Bioconcentration Factor 121 pH 1; Kutentha: 25 ° C (1) ACD
Bioconcentration Factor 2580 pH 2; Kutentha: 25 ° C (1) ACD
Bioconcentration Factor 23500 pH 3; Kutentha: 25 ° C (1) ACD
Bioconcentration Factor 71800 pH 4; Kutentha: 25 ° C (1) ACD
Bioconcentration Factor 89800 pH 5; Kutentha: 25 ° C (1) ACD
Bioconcentration Factor 92100 pH 6; Kutentha: 25 ° C (1) ACD
Bioconcentration Factor 91300 pH 7; Kutentha: 25 ° C (1) ACD
Bioconcentration Factor 82500 pH 8; Kutentha: 25 ° C (1) ACD
Bioconcentration Factor 42200 pH 9; Kutentha: 25 ° C (1) ACD
Bioconcentration Factor 7860 pH 10; Kutentha: 25 ° C (1) ACD

(1) Owerengedwa pogwiritsa ntchito Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Chemical

Katundu Mtengo Mkhalidwe Gwero
Koc 164 pH 1; Kutentha: 25 ° C (1) ACD
Koc 3480 pH 2; Kutentha: 25 ° C (1) ACD
Koc 31700 pH 3; Kutentha: 25 ° C (1) ACD
Koc 96900 pH 4; Kutentha: 25 ° C (1) ACD
Koc 1.21x105 pH 5; Kutentha: 25 ° C (1) ACD

 

Katundu Mtengo Mkhalidwe Gwero
Koc 1.24x105 pH 6; Kutentha: 25 ° C (1) ACD
Koc 1.23 x 105 pH 7; Kutentha: 25 ° C (1) ACD
Koc 1.11x105 pH 8; Kutentha: 25 ° C (1) ACD
Koc 56900 pH 9; Kutentha: 25 ° C (1) ACD
Koc 10600 pH 10; Kutentha: 25 ° C (1) ACD
logD 3.95 pH 1; Kutentha: 25 ° C (1) ACD
logD 5.28 pH 2; Kutentha: 25 ° C (1) ACD
logD 6.24 pH 3; Kutentha: 25 ° C (1) ACD
logD 6.73 pH 4; Kutentha: 25 ° C (1) ACD
logD 6.82 pH 5; Kutentha: 25 ° C (1) ACD
logD 6.83 pH 6; Kutentha: 25 ° C (1) ACD
logD 6.83 pH 7; Kutentha: 25 ° C (1) ACD
logD 6.79 pH 8; Kutentha: 25 ° C (1) ACD
logD 6.50 pH 9; Kutentha: 25 ° C (1) ACD
logD 5.77 pH 10; Kutentha: 25 ° C (1) ACD
logP 6.837±0.764 Kutentha: 25 ° C (1) ACD
Mass Intrinsic Solubility 4.4 x 10-4 g/L Kutentha: 25 ° C (1) ACD
Misa Solubility 0.34g/L pH 1; Kutentha: 25 ° C (1) ACD
Misa Solubility 0.016 g/L pH 2; Kutentha: 25 ° C (1) ACD
Misa Solubility 1.7 x 10-3 g/L pH 3; Kutentha: 25 ° C (1) ACD
Misa Solubility 5.7 x 10-4 g/L pH 4; Kutentha: 25 ° C (1) ACD
Misa Solubility 4.6 x 10-4 g/L pH 5; Kutentha: 25 ° C (1) ACD
Misa Solubility 4.4 x 10-4 g/L pH 6; Kutentha: 25 ° C (1) ACD
Misa Solubility 4.5 x 10-4 g/L pH 7; Kutentha: 25 ° C (1) ACD
Misa Solubility 4.9 x 10-4 g/L pH 8; Kutentha: 25 ° C (1) ACD
Misa Solubility 1.0 x 10-3 g/L pH 9; Kutentha: 25 ° C (1) ACD
Misa Solubility 5.2 x 10-3 g/L pH 10; Kutentha: 25 ° C (1) ACD
Misa Solubility 4.5 x 10-4 g/L Madzi Osasunthika pH 6.99; Kutentha: 25 ° C (1) ACD
Molar Intrinsic Solubility 4.8 x 10-7 mol / L Kutentha: 25 ° C (1) ACD
Molar Solubility 3.7 x 10-4 mol / L pH 1; Kutentha: 25 ° C (1) ACD
Molar Solubility 1.7 x 10-5 mol / L pH 2; Kutentha: 25 ° C (1) ACD
Molar Solubility 1.9 x 10-6 mol / L pH 3; Kutentha: 25 ° C (1) ACD

 

Katundu Mtengo Mkhalidwe Gwero
Molar Solubility 6.2 x 10-7 mol / L pH 4; Kutentha: 25 ° C (1) ACD
Molar Solubility 5.0 x 10-7 mol/L pH 5; Kutentha: 25 ° C (1) ACD
Molar Solubility 4.8 x 10-7 mol / L pH 6; Kutentha: 25 ° C (1) ACD
Molar Solubility 4.9 x 10-7 mol / L pH 7; Kutentha: 25 ° C (1) ACD
Molar Solubility 5.4 x 10-7 mol / L pH 8; Kutentha: 25 ° C (1) ACD
Molar Solubility 1.1 x 10-6 mol / L pH 9; Kutentha: 25 ° C (1) ACD
Molar Solubility 5.7 x 10-6 mol / L pH 10; Kutentha: 25 ° C (1) ACD
Molar Solubility 4.9 x 10-7 mol / L Madzi Osasunthika pH 6.99; Kutentha: 25 ° C (1) ACD
Kulemera kwa Maselo 914.00    
pKa 9.16±0.20 Kutentha Kwambiri kwa Acid: 25 ° C (1) ACD
pKa 3.45±0.70 Kutentha Kwambiri Kwambiri: 25 °C (1) ACD

(1) Owerengedwa pogwiritsa ntchito Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Lipinski

Katundu Mtengo Mkhalidwe Gwero
Ma Bond Osinthasintha Mwaulere 22   (1) ACD
H Olandira 17   (1) ACD
H Opereka 2   (1) ACD
H Chiwerengero cha Wopereka / Wolandira 19   (1) ACD
logP 6.837±0.764 Kutentha: 25 ° C (1) ACD
Kulemera kwa Maselo 914.00    

(1) Owerengedwa pogwiritsa ntchito Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Zogwirizana ndi Kapangidwe

Katundu Mtengo Condition Source
Malo a Polar Surface 203 a2 (1) ACD

(1) Owerengedwa pogwiritsa ntchito Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Zoneneratu za Spectra

Spectra ilipo
1H NMR
13 C NMR

Zowopsa za GHS

Gwero la Chidziwitso Chowopsa cha Code
H302 Zowopsa ngati zitamezedwa European Chemical Agency (ECHA) Classification & Labelling

Inventory - Gulu lodziwitsidwa ndi zilembo - zidziwitso zodziwika bwino, European Chemical Agency (ECHA)

Classification&Labelling Inventory - Gulu lodziwitsidwa ndi kulemba - zidziwitso zazikulu kwambiri


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