7-Amino-3-cephem-4-carboxylic acid

Zambiri Zoyambira:

Dzina lachingerezi:

7-ANCA;7-AMOCA;(6R,7R)-7-AMino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicAcid;7-NACA;7-NACA,7-ANCA;7-ANCAChemicalbookimpurity;CeftizoximeImpurity9;CeftizoximeImpurity16;Ceftizoximeintermediate(7-anca);7-amino-3-cephem-4-carboxylicacid

Nambala ya CAS: 36923-17-8

Mapangidwe a maselo: C7H8N2O3S

Molecular kulemera: 200.21

Nambala ya EINECS: 609-312-7

Zomangamanga:

Zogwirizana ndi magulu: Organic intermediates; Mankhwala apakatikati; Zopangira mankhwala.

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Physicochemical katundu

Malo osungunuka: 215-218 ° C

Malo otentha: 536.9±50.0 °C (Zonenedweratu)

Kachulukidwe: 1.69± 0.1g /cm3 (Zonenedweratu)

Refractive index: 1.735 (kuyerekeza)

Pothirira: 278.508°C

Kusungunuka: Kusungunuka mu acidic aqueous solution (pang'ono, kutentha), DMSO (pang'ono). Katundu: ufa woyera kapena woyera crystalline.

Kuthamanga kwa nthunzi: 0mmHg pa 25°C

Specification index

kufotokoza	unit	muyezo
Maonekedwe		White kapena woyera crystalline ufa
Zomwe zili zofunika kwambiri	%	≥98.5%
Chinyezi	%	≤1
Mono hybrid	%	≤0.5
Zochuluka	%	≤1

Product Application

Cephalosporin amagwiritsidwa ntchito ngati wapakatikati wa cefbutan ndi cefazoxime.

kupanga

sulfuric acid (104.3mL, 1.92mol) idawonjezedwa m'mabotolo atatu, kenako isophthalic acid (40g, 0.24mol) idawonjezedwa, kusonkhezeredwa ndi kutenthedwa mpaka 60 ℃, yosungidwa kwa 0.5h, ndi 60% nitric acid (37.8g, 0.36mol acceleration). Onjezani mu maola awiri. Pambuyo powonjezera, kutentha kusungirako ku 60 ℃ kwa maola awiri. Kuzizira mpaka pansi pa 50 ° C, kenaka yikani 100mL yamadzi. Zinthuzo zinali utakhazikika kutentha kwa firiji, anatsanulira mu fyuluta, amapopedwa kuchotsa zinyalala asidi, keke fyuluta anatsukidwa ndi madzi, chatsanulidwa kuti recrystallize, ndi mankhwala woyera anali 34,6 magalamu, zokolola anali 68,4%.

Kufotokozera ndi kusunga

20Kg kapena 25Kg/ ndowa, chidebe cha makatoni, chokhala ndi wosanjikiza woyera ndi thumba lakuda la polyethylene. 2 ℃-8 ℃ youma, malo ozizira, kutali ndi kusungirako kuwala, zomveka kwa zaka 2.

Zam'mbuyo: 5-nitroisophthalic acid

Ena: Bromosartan biphenyl

Lembani uthenga wanu apa ndikutumiza kwa ife